Hydrelo™ Allergy
Lubricant Eye Drops infused by natural
Ectoin® 2%

Hydrelo™ Allergy contains Ectoin®, a natural cell-protective molecule isolated from a bacteria that can survive under extreme conditions. This product alleviates dry eye symptoms by protecting against dehydration and forming a water-rich protective cover around eye structures. It also protects your eyes against the harmful effects of external factors and supports the regeneration process of conjunctiva.

Hydrelo™ Allergy can be used to treat and prevent symptoms of allergic conjunctivitis. It is effective in relieving itchy, red, and watery eyes.

Hydrelo™ Allergy is suitable for use in children.

  • Key benefits – Hydrelo™ Allergy contains natural Ectoin® which protects eyes against harmful allergens and relieves allergy symptoms
  • Natural active ingredient ECTOIN® - a natural water-binding substance that provides protection and reduces inflammation
  • Clinically proven (supported by studies)
    • Effectively reduces eye allergy symptoms
    • Protects from further dehydration and allergens
    • Reduces inflammation and supports healing of dry and irritated eyes
  • Preservative-free, suitable for everyday use
  • Suitable for contact lens wearers
  • How to use
  • Warnings
  • Single Dose: Detach one ampoule from the strip and open the unit by twisting off the tab, hold the ampoule upside down and let 1 or 2 drops fall into the pocket of each eye. Uses several time a day.

    Multiple Dose: Remove the protective cap of the bottle and avoid touching the exposed tip. Hold the bottle upside down, release one drop into the eye by gently squeezing the bottle. Carefully replace the protective cap after each usage of HydreloTM Allergy Lubricant Eye Drops.

    Do not use:

    • After the expiry date has passed
    • If you are sensitive to any ingredient in this product
  • If symptoms persist, please consult your doctor

    Keep out of reach of children

    There is no data available regarding interactions with other eye preparations There is no available data for use in pregnant or breastfeeding women

    Store between 2°C - 25°C

Grab & protect!

Available in single - pocket dose format so you can protect your eyes everywhere

Hydrelo™ Allergy efficacy is clinically proven

In a double-blind, randomized, cross-over study including 46 patients with allergic rhinitis and allergic conjunctivitis, Hydrelo™ Allergy showed significant and clinically relevant efficacy in reducing the ocular symptoms compared with placebo.

Hydrelo™ Allergy with natural Ectoin® significantly relieves the main eye allergy symptoms:

Changes in Ocular Symptom Score vs Baseline and vs Placebo2

Adapted from Internal data, bitop clinical studies.

*Denotes statistical significance

  • Baseline
  • Placebo
  • Ectoin®

Hydrelo™ contains natural Ectoin® for effective hydration and protection

About natural Ectoin®

  • Ectoin® is a natural ingredient and it was first isolated by a researcher, Professor Galinski from a bacteria named Ectothiorhodospira halochloris found in Wadi Natrun, Egypt.2,3
  • This bacteria is an “extremophile” and has the property to survive under extreme conditions like great heat or strong frost.

Water without Ectoin®

Water with Ectoin®

Adapted from Harishchandra RK et al. 2010 and Dwivedi M et al. 2014.

  • Water molecule
  • Protein
  • Ectoin®

How natural Ectoin® works to protect your eyes from dryness?

The eye surface is protected by a tear-film. The tear-film is composed by different types of layers including lipids (fat), water, and mucins (proteins). The water layer forms the majority of the tear-film.

Structure Of Tear Film

With kind permission from Allergan

Ectoin® is a natural water-binding substance which helps to maintain the tear-film stability forming an hydrating shield around the eyes.

  • Ectoin® stabilises the tear-film
  • Ectoin® hydrates the tear-film
  • Ectoin® reduces inflammation
  • Ectoin® protects the eye surface


  • 1. HydreloTM ALLERGY LUBRICANT EYE DROPS (Ectoin® 2%) Instructions for Use. Santen 2017.
  • 2. Internal data, clinical studies. Bitop. Santen.
  • 3. Imhoff JF et al. Isolation of extremely halophilic phototrophic bacteria from the alkaline Wadi Natrun, Egypt. Arch Hydrobiol 1978;84(3):381-388.
  • 4. HydreloTM LUBRICANT EYE DROPS (Ectoin® 0.5%) Instructions for Use. Santen 2017.
  • 5. Harishchandra RK et al. The effect of compatible solute ectoines on the structural organization of lipid monolayer and bilayer membranes. Biophys Chem 2010;150:37–46.
  • 6. Werkhauser N et al. Treatment of Allergic Rhinitis with Ectoine Containing Nasal Spray and Eye Drops in Comparison with Azelastine Containing Nasal Spray and Eye Drops or with Cromoglycic Acid Containing Nasal Spray. J Allergy 2014;1-13
  • 7. Dwivedi M et al. Biophysical in of the structure and function of the tear fluid lipid layers and the effect of ectoine. Part B: Artificial lipid films. Biochimica et Biophysica Acta 2014;1838(10):2716-2727.